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» Sequence Database Search Using Jumping Alignments
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105
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IPPS
2008
IEEE
15 years 9 months ago
Ordered index seed algorithm for intensive DNA sequence comparison
This paper presents a seed-based algorithm for intensive DNA sequence comparison. The novelty comes from the way seeds are used to efficiently generate small ungapped alignments ...
Dominique Lavenier
NAR
2008
119views more  NAR 2008»
15 years 2 months ago
MALISAM: a database of structurally analogous motifs in proteins
MALISAM (manual alignments for structurally analogous motifs) represents the first database containing pairs of structural analogs and their alignments. To find reliable analogs, ...
Hua Cheng, Bong-Hyun Kim, Nick V. Grishin
128
Voted
BMCBI
2010
133views more  BMCBI 2010»
15 years 2 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
143
Voted
BMCBI
2008
130views more  BMCBI 2008»
15 years 2 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
108
Voted
CISIS
2010
IEEE
15 years 9 months ago
Scalability Analysis of Progressive Alignment on a Multicore
—Sequence alignment is a fundamental instrument in Bioinformatics. In recent years, numerous proposals have been addressing the problem of accelerating this class of applications...
Sebastian Isaza, Friman Sánchez, Georgi Gay...