151 search results - page 16 / 31 » Sequence variation in ligand binding sites in proteins |
BMCBI
2010
13 years 7 months ago
2010
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
CSB
2003
IEEE
14 years 20 days ago
2003
IEEE
Regulatory sequence elements provide important clues to understanding and predicting gene expression. Although the binding sites for hundreds of transcription factors are known, t...
BMCBI
2006
13 years 7 months ago
2006
Background: The main aim of this study was to develop and implement an algorithm for the rapid, accurate and automated identification of paths leading from buried protein clefts, ...
BMCBI
2008
13 years 7 months ago
2008
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
BMCBI
2006
13 years 7 months ago
2006
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...