151 search results - page 4 / 31 » Sequence variation in ligand binding sites in proteins |
BMCBI
2010
13 years 7 months ago
2010
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
BMCBI
2005
13 years 7 months ago
2005
Background: Currently, the PDB contains approximately 29,000 protein structures comprising over 70,000 experimentally determined three-dimensional structures of over 5,000 differe...
BMCBI
2008
13 years 7 months ago
2008
Background: Protein structure prediction and computational protein design require efficient yet sufficiently accurate descriptions of aqueous solvent. We continue to evaluate the ...
BIBE
2010
IEEE
13 years 8 months ago
2010
IEEE
Studies of interactions between protein domains and ligands are important in many aspects such as cellular signaling and regulation. In this work, we applied a three-stage knowledg...
PRIB
2009
Springer
14 years 1 months ago
2009
Springer
Studies of interactions between protein domains and ligands are important in many aspects such as cellular signaling. We present a knowledge-guided approach for docking protein dom...