151 search results - page 5 / 31 » Sequence variation in ligand binding sites in proteins |
BMCBI
2011
12 years 11 months ago
2011
Background: While there are many methods for predicting protein-protein interaction, very few can determine the specific site of interaction on each protein. Characterization of t...
BMCBI
2010
13 years 7 months ago
2010
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
IJCNN
2006
IEEE
14 years 1 months ago
2006
IEEE
— The ability to identify protein binding sites and to detect specific amino acid residues that contribute to the specificity and affinity of protein interactions has importan...
BMCBI
2006
13 years 7 months ago
2006
Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
JCC
2011
12 years 10 months ago
2011
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...