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118
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BMCBI
2010
15 years 2 months ago
2010
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
129
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BMCBI
2010
15 years 2 months ago
2010
Background: Existing hidden Markov model decoding algorithms do not focus on approximately identifying the sequence feature boundaries. Results: We give a set of algorithms to com...
142
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BMCBI
2010
15 years 2 months ago
2010
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
140
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BMCBI
2010
15 years 2 months ago
2010
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
130
Voted
BMCBI
2010
15 years 2 months ago
2010
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...