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JCC
2008
88views more  JCC 2008»
13 years 7 months ago
A self-organizing algorithm for molecular alignment and pharmacophore development
Abstract: We present a method for simultaneous three-dimensional (3D) structure generation and pharmacophorebased alignment using a self-organizing algorithm called Stochastic Prox...
Deepak Bandyopadhyay, Dimitris K. Agrafiotis
BMCBI
2005
152views more  BMCBI 2005»
13 years 7 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
IOR
2002
112views more  IOR 2002»
13 years 7 months ago
Interdisciplinary Meandering in Science
abstract mathematics. My mentor was Professor S. Bochner, a distinguished contributor to harmonic analysis. My classmates included Richard Bellman (who later nurtured the method of...
Samuel Karlin
ORL
1998
116views more  ORL 1998»
13 years 7 months ago
Heuristic solution of the multisource Weber problem as a p-median problem
Good heuristic solutions for large Multisource Weber problems can be obtained by solving related p-median problems in which potential locations of the facilities are users location...
Pierre Hansen, Nenad Mladenovic, Éric D. Ta...
SIAMSC
2010
120views more  SIAMSC 2010»
13 years 6 months ago
Simultaneously Sparse Solutions to Linear Inverse Problems with Multiple System Matrices and a Single Observation Vector
Abstract. A problem that arises in slice-selective magnetic resonance imaging (MRI) radiofrequency (RF) excitation pulse design is abstracted as a novel linear inverse problem with...
Adam C. Zelinski, Vivek K. Goyal, Elfar Adalsteins...