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AIME
2009
Springer
13 years 5 months ago
Segmentation of Lung Tumours in Positron Emission Tomography Scans: A Machine Learning Approach
Lung cancer represents the most deadly type of malignancy. In this work we propose a machine learning approach to segmenting lung tumours in Positron Emission Tomography (PET) scan...
Aliaksei Kerhet, Cormac Small, Harvey Quon, Terenc...
BMCBI
2010
196views more  BMCBI 2010»
13 years 5 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...
BMCBI
2010
183views more  BMCBI 2010»
13 years 5 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...
BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
BIGSdb: Scalable analysis of bacterial genome variation at the population level
Background: The opportunities for bacterial population genomics that are being realised by the application of parallel nucleotide sequencing require novel bioinformatics platforms...
Keith A. Jolley, Martin C. J. Maiden
BMCBI
2010
259views more  BMCBI 2010»
13 years 2 months ago
Rule-based spatial modeling with diffusing, geometrically constrained molecules
Background: We suggest a new type of modeling approach for the coarse grained, particle-based spatial simulation of combinatorially complex chemical reaction systems. In our appro...
Gerd Gruenert, Bashar Ibrahim, Thorsten Lenser, Ma...