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ALMOB
2006
106views more  ALMOB 2006»
15 years 4 months ago
Multiple sequence alignment with user-defined anchor points
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...
BMCBI
2006
150views more  BMCBI 2006»
15 years 4 months ago
Instance-based concept learning from multiclass DNA microarray data
Background: Various statistical and machine learning methods have been successfully applied to the classification of DNA microarray data. Simple instance-based classifiers such as...
Daniel P. Berrar, Ian Bradbury, Werner Dubitzky
BMCBI
2006
122views more  BMCBI 2006»
15 years 4 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
BMCBI
2006
99views more  BMCBI 2006»
15 years 4 months ago
Genetic algorithm learning as a robust approach to RNA editing site prediction
Background: RNA editing is one of several post-transcriptional modifications that may contribute to organismal complexity in the face of limited gene complement in a genome. One f...
James Thompson, Shuba Gopal
BMCBI
2006
117views more  BMCBI 2006»
15 years 4 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...
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