In this paper we present a parallel implementation of T–Coffee — a widely used multiple sequence alignment package. Our software supports a majority of options provided by the...
Jaroslaw Zola, Xiao Yang, Adrian Rospondek, Sriniv...
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
Similarity search in sequence databases is of paramount importance in bioinformatics research. As the size of the genomic databases increases, similarity search of proteins in the...
Graphs are widely used for modeling complicated data, including chemical compounds, protein interactions, XML documents, and multimedia. Information retrieval against such data ca...
Haoliang Jiang, Haixun Wang, Philip S. Yu, Shuigen...
Hidden Markov Models are a widely used generative model for analysing sequence data. A variant, Profile Hidden Markov Models are a special case used in Bioinformatics to represent,...
Stefan Mutter, Bernhard Pfahringer, Geoffrey Holme...