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BIOINFORMATICS
2008
119views more  BIOINFORMATICS 2008»
13 years 9 months ago
Optimal design of thermally stable proteins
Motivation: For many biotechnological purposes, it is desirable to redesign proteins to be more structurally and functionally stable at higher temperatures. For example, chemical ...
Ryan M. Bannen, Vanitha Suresh, George N. Phillips...
BMCBI
2008
75views more  BMCBI 2008»
13 years 9 months ago
A three-state prediction of single point mutations on protein stability changes
Background: A basic question of protein structural studies is to which extent mutations affect the stability. This question may be addressed starting from sequence and/or from str...
Emidio Capriotti, Piero Fariselli, Ivan Rossi, Rit...
CLUSTER
2007
IEEE
14 years 3 months ago
Sequential and parallel implementation of a constraint-based algorithm for searching protein structures
— Data mining in biological structure libraries can be a powerful tool to better understand biochemical processes. This article introduces the LISA algorithm which enables the re...
Sascha Hunold, Thomas Rauber, Georg Wille
CEC
2009
IEEE
14 years 1 months ago
A parallel genetic algorithm for protein folding prediction using the 3D-HP Side Chain model
— This work presents a methodology for the application of a parallel genetic algorithm (PGA) to the problem of protein folding prediction, using the 3DHP-Side Chain model. This m...
César Manuel Vargas Benítez, Heitor ...
GECCO
2006
Springer
176views Optimization» more  GECCO 2006»
14 years 21 days ago
A genetic algorithm with backtracking for protein structure prediction
In this paper, we propose a simple genetic algorithm for finding the optimal conformation of a protein using the three-dimensional square HP model. A backtracking procedure is use...
Clayton Matthew Johnson, Anitha Katikireddy