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BMCBI
2005
75views more  BMCBI 2005»
13 years 8 months ago
Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
Background: The 'lid' subcomplex of the 26S proteasome and the COP9 signalosome (CSN complex) share a common architecture consisting of six subunits harbouring a so-call...
Hartmut Scheel, Kay Hofmann
BMCBI
2004
93views more  BMCBI 2004»
13 years 8 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
NAR
1998
73views more  NAR 1998»
13 years 8 months ago
Identification and characterization of the RAD51 gene from the ciliate Tetrahymena thermophila
The RAD51 gene is a eukaryotic homolog of recA, a critical component in homologous recombination and DNA repair pathways in Escherichia coli. We have cloned the RAD51 homolog from...
Colin Campbell, Daniel P. Romero
VLDB
2005
ACM
125views Database» more  VLDB 2005»
14 years 9 months ago
Sync your data: update propagation for heterogeneous protein databases
The traditional model of bench (wet) chemistry in many life sciences domain is today actively complimented by computer-based discoveries utilizing the growing number of online data...
Kajal T. Claypool, Elke A. Rundensteiner
BMCBI
2010
167views more  BMCBI 2010»
13 years 9 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...