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BMCBI
2004
158views more  BMCBI 2004»
13 years 7 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
DILS
2005
Springer
14 years 1 months ago
PLATCOM: Current Status and Plan for the Next Stages
We have been developing a system for comparing multiple genomes, PLATCOM, where users can choose genomes of their choice freely and perform analysis of the selected genomes with a...
Kwangmin Choi, Jeong-Hyeon Choi, Amit Saple, Zhipi...
BMCBI
2006
92views more  BMCBI 2006»
13 years 7 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
IPPS
2006
IEEE
14 years 1 months ago
Parallel implementation and performance characterization of MUSCLE
Multiple sequence alignment is a fundamental and very computationally intensive task in molecular biology. MUSCLE, a new algorithm for creating multiple alignments of protein sequ...
Xi Deng, Eric Li, Jiulong Shan, Wenguang Chen
HICSS
2003
IEEE
166views Biometrics» more  HICSS 2003»
14 years 1 months ago
Comparative Genome Annotation for Mapping, Prediction and Discovery of Genes
We have used comparative genome analyses to produce annotated maps for large genomic loci. The first example is a locus on mouse chromosome 9 that is syntenic to human chromosome ...
Claudia Kappen, J. Michael Salbaum