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BMCBI
2010
137views more  BMCBI 2010»
13 years 7 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
ISMB
1997
13 years 9 months ago
Prediction of Enzyme Classification from Protein Sequence without the Use of Sequence Similarity
1 W’edescribe a novel approach for predicting the function of a protein from its amino-acid sequence. Given features that can be computedfrom the amino-acid sequence in a straigh...
Marie desJardins, Peter D. Karp, Markus Krummenack...
ISVD
2007
IEEE
14 years 1 months ago
Decoy Discrimination Using Contact Potentials Based on Delaunay Tessellation of Hydrated Proteins
Three strategies are presented for developing a knowledge-based statistical contact potential from computationally hydrated proteins that may be useful in studies of protein foldi...
Gregory M. Reck, Iosif I. Vaisman
BIBE
2003
IEEE
133views Bioinformatics» more  BIBE 2003»
14 years 27 days ago
A Computational Pipeline for Protein Structure Prediction and Analysis at Genome Scale
The tertiary (3D) structure of a protein contains the essential information for understanding the biological function of the protein at the molecular and cellular levels. Traditio...
Manesh J. Shah, Sergei Passovets, Dongsup Kim, Kyl...
NAR
1998
161views more  NAR 1998»
13 years 7 months ago
Touring protein fold space with Dali/FSSP
The FSSP database and its new supplement, the Dali Domain Dictionary, present a continuously updated classification of all known 3D protein structures. The classification is deriv...
Liisa Holm, Chris Sander