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WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
14 years 1 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
ROCAI
2004
Springer
14 years 29 days ago
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve
We introduce a model class for statistical learning which is based on mixtures of propositional rules. In our mixture model, the weight of a rule is not uniform over the entire ins...
Tobias Sing, Niko Beerenwinkel, Thomas Lengauer
KDD
1998
ACM
140views Data Mining» more  KDD 1998»
13 years 12 months ago
Blurring the Distinction between Command and Data in Scientific KDD
We have been working on two different KDD systems for scientific data. One system involves comparative genomics, where the database contains more than 60,000 plant gene and protei...
John V. Carlis, Elizabeth Shoop, Scott Krieger
ISMB
2007
13 years 10 months ago
A Chado case study: an ontology-based modular schema for representing genome-associated biological information
Motivation: A few years ago, FlyBase undertook to design a new database schema to store Drosophila data. It would fully integrate genomic sequence and annotation data with bibliog...
Chris Mungall, David B. Emmert
ALMOB
2008
160views more  ALMOB 2008»
13 years 7 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich