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BMCBI
2006
106views more  BMCBI 2006»
13 years 10 months ago
Prediction of the functional class of metal-binding proteins from sequence derived physicochemical properties by support vector
Metal-binding proteins play important roles in structural stability, signaling, regulation, transport, immune response, metabolism control, and metal homeostasis. Because of their...
H. H. Lin, L. Y. Han, H. L. Zhang, C. J. Zheng, B....
NAR
1998
86views more  NAR 1998»
13 years 9 months ago
Pfam: multiple sequence alignments and HMM-profiles of protein domains
Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The definition of domain boundaries, family members and alignm...
Erik L. L. Sonnhammer, Sean R. Eddy, Ewan Birney, ...
ISMB
1993
13 years 11 months ago
Transmembrane Segment Prediction from Protein Sequence Data
Weconsider tile automatedidentification of transmembrane domains in membrane protein sequences. 324 proteins (containing 1585 segrrmnts) werc examined, representing every protein ...
Sholom M. Weiss, Dawn M. Cohen, Nitin Indurkhya
BMCBI
2008
99views more  BMCBI 2008»
13 years 10 months ago
NestedMICA as an ab initio protein motif discovery tool
Background: Discovering overrepresented patterns in amino acid sequences is an important step in protein functional element identification. We adapted and extended NestedMICA, an ...
Mutlu Dogruel, Thomas A. Down, Tim J. P. Hubbard
NAR
2008
122views more  NAR 2008»
13 years 10 months ago
SIMAP - structuring the network of protein similarities
Protein sequences are the most important source of evolutionary and functional information for new proteins. In order to facilitate the computationally intensive tasks of sequence...
Thomas Rattei, Patrick Tischler, Roland Arnold, Fr...