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» Shotgun Protein Sequencing
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BMCBI
2010
133views more  BMCBI 2010»
13 years 10 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
BMCBI
2005
114views more  BMCBI 2005»
13 years 9 months ago
Extension of Lander-Waterman theory for sequencing filtered DNA libraries
Background: The degree to which conventional DNA sequencing techniques will be successful for highly repetitive genomes is unclear. Investigators are therefore considering various...
Michael C. Wendl, W. Bradley Barbazuk
BMCBI
2010
153views more  BMCBI 2010»
13 years 9 months ago
Pash 3.0: A versatile software package for read mapping and integrative analysis of genomic and epigenomic variation using massi
Background: Massively parallel sequencing readouts of epigenomic assays are enabling integrative genome-wide analyses of genomic and epigenomic variation. Pash 3.0 performs sequen...
Cristian Coarfa, Fuli Yu, Christopher A. Miller, Z...
AINA
2006
IEEE
14 years 1 months ago
Accelerating HMMer searches on Opteron processors with minimally invasive recoding
HMMer is a widely used tool for protein sequence homology detection, as well as functional annotation of homologous protein sequences, and protein family classification. The HMMer...
Joseph I. Landman, Joydeep Ray, John Paul Walters
BMCBI
2006
109views more  BMCBI 2006»
13 years 10 months ago
A computational approach to discovering the functions of bacterial phytochromes by analysis of homolog distributions
Background: Phytochromes are photoreceptors, discovered in plants, that control a wide variety of developmental processes. They have also been found in bacteria and fungi, but for...
Tilman Lamparter