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» Shotgun Protein Sequencing
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RECOMB
2003
Springer
14 years 10 months ago
Haplotype reconstruction from SNP alignment
In this paper, we describe a method for statistical reconstruction of haplotypes from a set of aligned SNP fragments. We consider the case of a pair of homologous human chromosome...
Lei Li, Jong Hyun Kim, Michael S. Waterman
NAR
2008
152views more  NAR 2008»
13 years 10 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin
SAC
2005
ACM
14 years 3 months ago
Comparing approaches to predict transmembrane domains in protein sequences
There are today several systems for predicting transmembrane domains in membrane protein sequences. As they are based on different classifiers as well as different pre- and post-p...
Paul Davidsson, Johan Hagelbäck, Kenny Svenss...
BMCBI
2008
88views more  BMCBI 2008»
13 years 10 months ago
Use of machine learning algorithms to classify binary protein sequences as highly-designable or poorly-designable
Background: By using a standard Support Vector Machine (SVM) with a Sequential Minimal Optimization (SMO) method of training, Na
Myron Peto, Andrzej Kloczkowski, Vasant Honavar, R...
BMCBI
2008
114views more  BMCBI 2008»
13 years 10 months ago
Combining classifiers for improved classification of proteins from sequence or structure
Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...