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» Shotgun Protein Sequencing
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VLDB
2002
ACM
83views Database» more  VLDB 2002»
13 years 9 months ago
Searching on the Secondary Structure of Protein Sequences
In spite of the many decades of progress in database research, surprisingly scientists in the life sciences community still struggle with inefficient and awkward tools for queryin...
Laurie Hammel, Jignesh M. Patel
BMCBI
2008
124views more  BMCBI 2008»
13 years 10 months ago
Computational identification of ubiquitylation sites from protein sequences
Background: Ubiquitylation plays an important role in regulating protein functions. Recently, experimental methods were developed toward effective identification of ubiquitylation...
Chun-Wei Tung, Shinn-Ying Ho
BMCBI
2006
159views more  BMCBI 2006»
13 years 10 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
BMCBI
2006
85views more  BMCBI 2006»
13 years 10 months ago
Identification of physicochemical selective pressure on protein encoding nucleotide sequences
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
13 years 8 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung