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BMCBI
2005
114views more  BMCBI 2005»
13 years 8 months ago
Extension of Lander-Waterman theory for sequencing filtered DNA libraries
Background: The degree to which conventional DNA sequencing techniques will be successful for highly repetitive genomes is unclear. Investigators are therefore considering various...
Michael C. Wendl, W. Bradley Barbazuk
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
Pash 3.0: A versatile software package for read mapping and integrative analysis of genomic and epigenomic variation using massi
Background: Massively parallel sequencing readouts of epigenomic assays are enabling integrative genome-wide analyses of genomic and epigenomic variation. Pash 3.0 performs sequen...
Cristian Coarfa, Fuli Yu, Christopher A. Miller, Z...
BIBM
2010
IEEE
286views Bioinformatics» more  BIBM 2010»
13 years 6 months ago
Evaluation of short read metagenomic assembly
Advances in sequencing technologies have equipped researchers with the ability to sequence the collective genome of entire microbial communities commonly referred to as metagenomi...
Anveshi Charuvaka, Huzefa Rangwala
GCB
2010
Springer
182views Biometrics» more  GCB 2010»
13 years 6 months ago
Repeat-aware Comparative Genome Assembly
: The current high-throughput sequencing technologies produce gigabytes of data even when prokaryotic genomes are processed. In a subsequent assembly phase, the generated overlappi...
Peter Husemann, Jens Stoye
BMCBI
2011
13 years 6 days ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...