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BMCBI
2008
99views more  BMCBI 2008»
13 years 7 months ago
Binning sequences using very sparse labels within a metagenome
Background: In metagenomic studies, a process called binning is necessary to assign contigs that belong to multiple species to their respective phylogenetic groups. Most of the cu...
Chon-Kit Kenneth Chan, Arthur L. Hsu, Saman K. Hal...
BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
13 years 7 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
BMCBI
2008
146views more  BMCBI 2008»
13 years 7 months ago
Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
Jean-François Taly, Antoine Marin, Jean-Fra...
ARTMED
2006
86views more  ARTMED 2006»
13 years 7 months ago
Spatiotemporal reasoning about epidemiological data
Objective. In this article, we propose new methods to visualize and reason about spatiotemporal epidemiological data. Background. Efficient computerized reasoning about epidemics ...
Peter Z. Revesz, Shasha Wu
BMCBI
2007
104views more  BMCBI 2007»
13 years 7 months ago
Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary conservation
Background: The translational efficiency of an mRNA can be modulated by upstream open reading frames (uORFs) present in certain genes. A uORF can attenuate translation of the main...
Marija Cvijovic, Daniel Dalevi, Elizabeth Bilsland...