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» Simple Models for Scaling in Phylogenetic Trees
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BMCBI
2008
91views more  BMCBI 2008»
13 years 8 months ago
t2prhd: a tool to study the patterns of repeat evolution
Background: The models developed to characterize the evolution of multigene families (such as the birth-and-death and the concerted models) have also been applied on the level of ...
Botond Sipos, Kálmán Somogyi, Istv&a...
BMCBI
2006
120views more  BMCBI 2006»
13 years 8 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
ICML
2006
IEEE
14 years 9 months ago
A graphical model for predicting protein molecular function
We present a simple statistical model of molecular function evolution to predict protein function. The model description encodes general knowledge of how molecular function evolve...
Barbara E. Engelhardt, Michael I. Jordan, Steven E...
BMCBI
2011
13 years 3 months ago
N-gram analysis of 970 microbial organisms reveals presence of biological language models
Background: It has been suggested previously that genome and proteome sequences show characteristics typical of natural-language texts such as “signature-style” word usage ind...
Hatice U. Osmanbeyoglu, Madhavi Ganapathiraju
MASCOTS
2003
13 years 10 months ago
Small-World Characteristics of the Internet and Multicast Scaling
Recent work has shown that the physical connectivity of the Internet exhibits small-world behavior. Characterizing such behavior is important not only for generating realistic Int...
Shudong Jin, Azer Bestavros