Background: G protein-coupled receptors (GPCRs) represent a family of well-characterized drug targets with significant therapeutic value. Phylogenetic classifications may help to ...
Eelke van der Horst, Julio E. Peironcely, Adriaan ...
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
Saskia de Groot, Thomas Mailund, Gerton Lunter, Jo...
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...
Background: Generally speaking, different classifiers tend to work well for certain types of data and conversely, it is usually not known a priori which algorithm will be optimal ...