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BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
BMCBI
2008
119views more  BMCBI 2008»
13 years 8 months ago
Integrated multi-level quality control for proteomic profiling studies using mass spectrometry
Background: Proteomic profiling using mass spectrometry (MS) is one of the most promising methods for the analysis of complex biological samples such as urine, serum and tissue fo...
David A. Cairns, David N. Perkins, Anthea J. Stanl...
BMCBI
2008
164views more  BMCBI 2008»
13 years 8 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
BMCBI
2008
208views more  BMCBI 2008»
13 years 8 months ago
GraphFind: enhancing graph searching by low support data mining techniques
Background: Biomedical and chemical databases are large and rapidly growing in size. Graphs naturally model such kinds of data. To fully exploit the wealth of information in these...
Alfredo Ferro, Rosalba Giugno, Misael Mongiov&igra...
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