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» Smoothing Gene Expression Using Biological Networks
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BMCBI
2010
91views more  BMCBI 2010»
13 years 7 months ago
Algorithm-driven Artifacts in median polish summarization of Microarray data
Background: High-throughput measurement of transcript intensities using Affymetrix type oligonucleotide microarrays has produced a massive quantity of data during the last decade....
Federico M. Giorgi, Anthony M. Bolger, Marc Lohse,...
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BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Correction of scaling mismatches in oligonucleotide microarray data
Background: Gene expression microarray data is notoriously subject to high signal variability. Moreover, unavoidable variation in the concentration of transcripts applied to micro...
Martino Barenco, Jaroslav Stark, Daniel Brewer, Da...
BMCBI
2008
171views more  BMCBI 2008»
13 years 7 months ago
Fuzzy association rules for biological data analysis: A case study on yeast
Background: Last years' mapping of diverse genomes has generated huge amounts of biological data which are currently dispersed through many databases. Integration of the info...
Francisco J. Lopez, Armando Blanco, Fernando Garci...
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
A method for computing the overall statistical significance of a treatment effect among a group of genes
Background: In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be ...
Robert R. Delongchamp, Taewon Lee, Cruz Velasco
IPPS
2003
IEEE
14 years 1 months ago
Parallel Detection of Regulatory Elements with gMP
The detection of regulatory elements from a large set of regulatory regions is a challenging problem in computational genomics. However, computational methods to extract this biol...
Bertil Schmidt, Lin Feng, Amey V. Laud, Yusdi Sant...