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» Smoothing Gene Expression Using Biological Networks
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GECCO
2009
Springer
14 years 2 months ago
Multiobjectivization for parameter estimation: a case-study on the segment polarity network of drosophila
Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimati...
Tim Hohm, Eckart Zitzler
JIB
2006
220views more  JIB 2006»
13 years 7 months ago
An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
IWANN
2009
Springer
14 years 2 months ago
Biomedical Text Mining Applied to Document Retrieval and Semantic Indexing
In Biomedical research, the ability to retrieve the adequate information from the ever growing literature is an extremely important asset. This work provides an enhanced and genera...
Anália Lourenço, Sónia Carnei...
CSB
2003
IEEE
14 years 25 days ago
Initial Large-scale Exploration of Protein-protein Interactions in Human Brain
Study of protein interaction networks is crucial to post-genomic systems biology. Aided by highthroughput screening technologies, biologists are rapidly accumulating protein-prote...
Jake Yue Chen, Andrey Y. Sivachenko, Russell Bell,...
BMCBI
2006
74views more  BMCBI 2006»
13 years 7 months ago
Protein protein interactions, evolutionary rate, abundance and age
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
Ramazan Saeed, Charlotte M. Deane