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» Smoothing Gene Expression Using Biological Networks
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SP
2008
IEEE
122views Security Privacy» more  SP 2008»
13 years 7 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...
BMCBI
2004
150views more  BMCBI 2004»
13 years 7 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
AAAI
2008
13 years 9 months ago
Generating Application-Specific Benchmark Models for Complex Systems
Automated generators for synthetic models and data can play a crucial role in designing new algorithms/modelframeworks, given the sparsity of benchmark models for empirical analys...
Jun Wang, Gregory M. Provan
BMCBI
2006
181views more  BMCBI 2006»
13 years 7 months ago
The comprehensive updated regulatory network of Escherichia coli K-12
Background: Escherichia coli is the model organism for which our knowledge of its regulatory network is the most extensive. Over the last few years, our project has been collectin...
Heladia Salgado, Alberto Santos-Zavaleta, Socorro ...
EVOW
2010
Springer
13 years 6 months ago
Finding Gapped Motifs by a Novel Evolutionary Algorithm
Background: Identifying approximately repeated patterns, or motifs, in DNA sequences from a set of co-regulated genes is an important step towards deciphering the complex gene reg...
Chengwei Lei, Jianhua Ruan