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» Smoothing Gene Expression Using Biological Networks
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BMCBI
2010
109views more  BMCBI 2010»
13 years 9 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
TCBB
2010
136views more  TCBB 2010»
13 years 7 months ago
Integrating Data Clustering and Visualization for the Analysis of 3D Gene Expression Data
— The recent development of methods for extracting precise measurements of spatial gene expression patterns from three-dimensional (3D) image data opens the way for new analyses ...
Oliver Rübel, Gunther H. Weber, Min-Yu Huang,...
BMCBI
2010
160views more  BMCBI 2010»
13 years 9 months ago
Extracting consistent knowledge from highly inconsistent cancer gene data sources
Background: Hundreds of genes that are causally implicated in oncogenesis have been found and collected in various databases. For efficient application of these abundant but diver...
Xue Gong, Ruihong Wu, Yuannv Zhang, Wenyuan Zhao, ...
BMCBI
2005
107views more  BMCBI 2005»
13 years 8 months ago
Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach
Background: In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and with...
Jun Lu, John K. Tomfohr, Thomas B. Kepler
DILS
2005
Springer
14 years 2 months ago
Integrating Heterogeneous Microarray Data Sources Using Correlation Signatures
Abstract. Microarrays are one of the latest breakthroughs in experimental molecular biology. Thousands of different research groups generate tens of thousands of microarray gene e...
Jaewoo Kang, Jiong Yang, Wanhong Xu, Pankaj Chopra