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119
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BMCBI
2010
112views more  BMCBI 2010»
15 years 3 months ago
In silico fragmentation for computer assisted identification of metabolite mass spectra
Background: Mass spectrometry has become the analytical method of choice in metabolomics research. The identification of unknown compounds is the main bottleneck. In addition to t...
Sebastian Wolf, Stephan Schmidt, Matthias Mül...
129
Voted
BMCBI
2010
100views more  BMCBI 2010»
15 years 3 months ago
Partitioning of copy-number genotypes in pedigrees
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
Louis-Philippe Lemieux Perreault, Gregor U. Andelf...
132
Voted
BMCBI
2010
142views more  BMCBI 2010»
15 years 3 months ago
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
Frederick A. Matsen III, Robin B. Kodner, E. Virgi...
118
Voted
BMCBI
2010
112views more  BMCBI 2010»
15 years 3 months ago
SeqAnt: A web service to rapidly identify and annotate DNA sequence variations
Background: The enormous throughput and low cost of second-generation sequencing platforms now allow research and clinical geneticists to routinely perform single experiments that...
Amol Carl Shetty, Prashanth Athri, Kajari Mondal, ...
132
Voted
BMCBI
2008
113views more  BMCBI 2008»
15 years 3 months ago
SynBlast: Assisting the analysis of conserved synteny information
Motivation: In the last years more than 20 vertebrate genomes have been sequenced, and the rate at which genomic DNA information becomes available is rapidly accelerating. Gene du...
Jörg Lehmann, Peter F. Stadler, Sonja J. Proh...
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