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BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
Benedikt Zacher, Pei Fen Kuan, Achim Tresch
BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
The IronChip evaluation package: a package of perl modules for robust analysis of custom microarrays
Background: Gene expression studies greatly contribute to our understanding of complex relationships in gene regulatory networks. However, the complexity of array design, producti...
Yevhen Vainshtein, Mayka Sanchez, Alvis Brazma, Ma...
BMCBI
2008
108views more  BMCBI 2008»
13 years 8 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
ALMOB
2006
113views more  ALMOB 2006»
13 years 8 months ago
Inverse bifurcation analysis: application to simple gene systems
Background: Bifurcation analysis has proven to be a powerful method for understanding the qualitative behavior of gene regulatory networks. In addition to the more traditional for...
James Lu, Heinz W. Engl, Peter Schuster
JKM
2006
135views more  JKM 2006»
13 years 8 months ago
Learning from the Mars Rover Mission: scientific discovery, learning and memory
Purpose Knowledge management for space exploration is part of a multi-generational effort. Each mission builds on knowledge from prior missions, and learning is the first step in ...
Charlotte Linde