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» Solutions to Computational Problems Through Gene Assembly
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BCS
2008
13 years 9 months ago
Beatbox - A Computer Simulation Environment for Computational Biology of the Heart
Despite over a century's study, the trigger mechanisms of cardiac arrhythmias are poorly understood. Even modern experimental methods do not provide sufficient temporal and s...
Ross McFarlane, Irina V. Biktasheva
BMCBI
2006
113views more  BMCBI 2006»
13 years 7 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
ECCV
2008
Springer
14 years 6 months ago
Toward Global Minimum through Combined Local Minima
There are many local and greedy algorithms for energy minimization over Markov Random Field (MRF) such as iterated condition mode (ICM) and various gradient descent methods. Local ...
Ho Yub Jung, Kyoung Mu Lee, Sang Uk Lee
RE
2002
Springer
13 years 7 months ago
Relating Software Requirements and Architectures Using Problem Frames
Problem frames provide a means of analyzing and decomposing problems. They emphasise the world outside of the computer, helping the developer to focus on the problem domain, inste...
Jon G. Hall, Michael Jackson, Robin C. Laney, Bash...
RE
2004
Springer
14 years 1 months ago
Architecture-driven Problem Decomposition
Jackson’s Problem Frames provide a means of analysing and decomposing problems. They emphasise the world outside the computer helping the developer to focus on the problem domai...
Lucia Rapanotti, Jon G. Hall, Michael Jackson, Bas...