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133
Voted
BMCBI
2010
15 years 2 months ago
2010
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
151
Voted
BMCBI
2008
15 years 2 months ago
2008
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
132
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BMCBI
2010
15 years 2 months ago
2010
Background: There is an increasing demand to assemble and align large-scale biological sequence data sets. The commonly used multiple sequence alignment programs are still limited...
123
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BMCBI
2008
15 years 2 months ago
2008
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
BMCBI
2008
15 years 2 months ago
2008
Background: Although fold change is a commonly used criterion in quantitative proteomics for differentiating regulated proteins, it does not provide an estimation of false positiv...