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» Some Notes on Models and Modelling
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BMCBI
2006
239views more  BMCBI 2006»
13 years 7 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2006
99views more  BMCBI 2006»
13 years 7 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shoc
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
Ester Vilaprinyó, Rui Alves, Albert Sorriba...
HEURISTICS
2008
124views more  HEURISTICS 2008»
13 years 7 months ago
A variable neighborhood search for the capacitated arc routing problem with intermediate facilities
In this talk we present a unified Variable Neighborhood Search (VNS) algorithm for the Capacitated Arc Routing Problem (CARP) and some of its variants - the Capacitated Arc Routin...
Michael Polacek, Karl F. Doerner, Richard F. Hartl...
BMCBI
2006
165views more  BMCBI 2006»
13 years 7 months ago
A stable gene selection in microarray data analysis
Background: Microarray data analysis is notorious for involving a huge number of genes compared to a relatively small number of samples. Gene selection is to detect the most signi...
Kun Yang, Zhipeng Cai, Jianzhong Li, Guohui Lin
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