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BMCBI
2010
130views more  BMCBI 2010»
13 years 9 months ago
Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Karel Zimmermann, Jean-François Gibrat
BMCBI
2010
134views more  BMCBI 2010»
13 years 9 months ago
Semi-automated screening of biomedical citations for systematic reviews
Background: Systematic reviews address a specific clinical question by unbiasedly assessing and analyzing the pertinent literature. Citation screening is a time-consuming and crit...
Byron C. Wallace, Thomas A. Trikalinos, Joseph Lau...
BMCBI
2008
128views more  BMCBI 2008»
13 years 9 months ago
Nonparametric relevance-shifted multiple testing procedures for the analysis of high-dimensional multivariate data with small sa
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
Cornelia Frömke, Ludwig A. Hothorn, Siegfried...
BMCBI
2008
228views more  BMCBI 2008»
13 years 9 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye
BMCBI
2008
214views more  BMCBI 2008»
13 years 9 months ago
Accelerating String Set Matching in FPGA Hardware for Bioinformatics Research
Background: This paper describes techniques for accelerating the performance of the string set matching problem with particular emphasis on applications in computational proteomic...
Yoginder S. Dandass, Shane C. Burgess, Mark Lawren...
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