Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
Long-range correlations in genomic base composition are a ubiquitous statistical feature among many eukaryotic genomes. In this article, these correlations are shown to substantia...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
The accuracy and scalability of multiple sequence alignment (MSA) of DNAs and proteins have long been and are still important issues in bioinformatics. To rapidly construct a reas...
Pairwise sequence alignment is a fundamental operation for homology search in bioinformatics. For two DNA or protein sequences of length ¢ and £ , full-matrix (FM), dynamic prog...
Adrian Driga, Paul Lu, Jonathan Schaeffer, Duane S...
This statement of interest presents a brief rationale and description of issues for using ontology alignment as a key step in dynamically chaining together a sequence of web servic...