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» Spatio-Temporal Alignment of Sequences
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DM
2010
97views more  DM 2010»
13 years 9 months ago
Random preorders and alignments
A preorder consists of linearly ordered equivalence classes called blocks, and an alignment is a sequence of cycles on n labelled elements. We investigate the block structure of a...
Peter J. Cameron, Mihyun Kang, Dudley Stark
BMCBI
2006
117views more  BMCBI 2006»
13 years 9 months ago
Incorporating background frequency improves entropy-based residue conservation measures
Background: Several entropy-based methods have been developed for scoring sequence conservation in protein multiple sequence alignments. High scoring amino acid positions may corr...
Kai Wang, Ram Samudrala
BMCBI
2005
109views more  BMCBI 2005»
13 years 9 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
BMCBI
2008
109views more  BMCBI 2008»
13 years 9 months ago
ConStruct: Improved construction of RNA consensus structures
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
Andreas Wilm, Kornelia Linnenbrink, Gerhard Steger
CORR
2007
Springer
81views Education» more  CORR 2007»
13 years 9 months ago
Faster exon assembly by sparse spliced alignment
Assembling a gene from candidate exons is an important problem in computational biology. Among the most successful approaches to this problem is spliced alignment, proposed by Gelf...
Alexandre Tiskin