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» Species-specific protein sequence and fold optimizations
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EUROGP
2005
Springer
14 years 1 months ago
Evolving L-Systems to Capture Protein Structure Native Conformations
Abstract. A protein is a linear chain of amino acids that folds into a unique functional structure, called its native state. In this state, proteins show repeated substructures lik...
Gabi Escuela, Gabriela Ochoa, Natalio Krasnogor
BMCBI
2006
132views more  BMCBI 2006»
13 years 7 months ago
Length-dependent prediction of protein intrinsic disorder
Background: Due to the functional importance of intrinsically disordered proteins or protein regions, prediction of intrinsic protein disorder from amino acid sequence has become ...
Kang Peng, Predrag Radivojac, Slobodan Vucetic, A....
BIBE
2006
IEEE
112views Bioinformatics» more  BIBE 2006»
14 years 1 months ago
Finding Correlations in Functionally Equivalent Proteins by Integrating Automated and Visual Data Exploration
The analysis of alignments of functionally equivalent proteins can reveal regularities such as correlated positions or residue patterns which are important to ensure a specific f...
Daniel A. Keim, Daniela Oelke, Royal Truman, Klaus...
BIBE
2008
IEEE
142views Bioinformatics» more  BIBE 2008»
14 years 2 months ago
Optimizing performance, cost, and sensitivity in pairwise sequence search on a cluster of PlayStations
— The Smith-Waterman algorithm is a dynamic programming method for determining optimal local alignments between nucleotide or protein sequences. However, it suffers from quadrati...
Ashwin M. Aji, Wu-chun Feng
GECCO
2009
Springer
190views Optimization» more  GECCO 2009»
13 years 11 months ago
Genetic programming for protein related text classification
Since the genomics revolution, bioinformatics has never been so popular. Many researchers have investigated with great success the use of evolutionary computation in bioinformatic...
Marc Segond, Cyril Fonlupt, Denis Robilliard