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BMCBI
2005
130views more  BMCBI 2005»
13 years 9 months ago
Squid - a simple bioinformatics grid
Background: BLAST is a widely used genetic research tool for analysis of similarity between nucleotide and protein sequences. This paper presents a software application entitled &...
Paulo C. Carvalho, Rafael V. Glória, Antoni...
BMCBI
2005
142views more  BMCBI 2005»
13 years 9 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
BMCBI
2005
131views more  BMCBI 2005»
13 years 9 months ago
Functional annotation by identification of local surface similarities: a novel tool for structural genomics
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
Fabrizio Ferrè, Gabriele Ausiello, Andreas ...
BMCBI
2005
201views more  BMCBI 2005»
13 years 8 months ago
A comparative study of discriminating human heart failure etiology using gene expression profiles
Background: Human heart failure is a complex disease that manifests from multiple genetic and environmental factors. Although ischemic and non-ischemic heart disease present clini...
Xiaohong Huang, Wei Pan, Suzanne Grindle, Xinqiang...
BMCBI
2005
198views more  BMCBI 2005»
13 years 8 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
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