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BMCBI
2010
106views more  BMCBI 2010»
13 years 10 months ago
Predicting MHC class I epitopes in large datasets
Background: Experimental screening of large sets of peptides with respect to their MHC binding capabilities is still very demanding due to the large number of possible peptide seq...
Kirsten Roomp, Iris Antes, Thomas Lengauer
BMCBI
2010
109views more  BMCBI 2010»
13 years 10 months ago
Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
Andrew J. Bordner, Hans D. Mittelmann
ICCAD
2006
IEEE
103views Hardware» more  ICCAD 2006»
14 years 6 months ago
A statistical framework for post-silicon tuning through body bias clustering
Adaptive body biasing (ABB) is a powerful technique that allows post-silicon tuning of individual manufactured dies such that each die optimally meets the delay and power constrai...
Sarvesh H. Kulkarni, Dennis Sylvester, David Blaau...
BMCBI
2006
116views more  BMCBI 2006»
13 years 10 months ago
Whole genome association mapping by incompatibilities and local perfect phylogenies
Background: With current technology, vast amounts of data can be cheaply and efficiently produced in association studies, and to prevent data analysis to become the bottleneck of ...
Thomas Mailund, Søren Besenbacher, Mikkel H...
BMCBI
2010
110views more  BMCBI 2010»
13 years 10 months ago
Missing value imputation for epistatic MAPs
Background: Epistatic miniarray profiling (E-MAPs) is a high-throughput approach capable of quantifying aggravating or alleviating genetic interactions between gene pairs. The dat...
Colm Ryan, Derek Greene, Gerard Cagney, Padraig Cu...