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BMCBI
2008
75views more  BMCBI 2008»
13 years 8 months ago
A three-state prediction of single point mutations on protein stability changes
Background: A basic question of protein structural studies is to which extent mutations affect the stability. This question may be addressed starting from sequence and/or from str...
Emidio Capriotti, Piero Fariselli, Ivan Rossi, Rit...
ISAAC
2004
Springer
106views Algorithms» more  ISAAC 2004»
14 years 1 months ago
Minimum Common String Partition Problem: Hardness and Approximations
String comparison is a fundamental problem in computer science, with applications in areas such as computational biology, text processing or compression. In this paper we address t...
Avraham Goldstein, Petr Kolman, Jie Zheng
BMCBI
2005
133views more  BMCBI 2005»
13 years 7 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
RECOMB
2005
Springer
14 years 8 months ago
Information Theoretic Approaches to Whole Genome Phylogenies
We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our me...
David Burstein, Igor Ulitsky, Tamir Tuller, Benny ...
BMCBI
2011
12 years 11 months ago
Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics
Background: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expressio...
Tracy L. Bergemann, Jason Wilson