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» Statistical Analysis of Long-Range Interactions in Proteins
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EXPERT
2002
146views more  EXPERT 2002»
13 years 7 months ago
The Frame-Based Module of the SUISEKI Information Extraction System
names in the same abstract already indicates a relation between them. Because of its simplicity, we can apply this approach to large amounts of text and establish interaction netwo...
Christian Blaschke, Alfonso Valencia
BIBE
2006
IEEE
112views Bioinformatics» more  BIBE 2006»
14 years 1 months ago
Finding Correlations in Functionally Equivalent Proteins by Integrating Automated and Visual Data Exploration
The analysis of alignments of functionally equivalent proteins can reveal regularities such as correlated positions or residue patterns which are important to ensure a specific f...
Daniel A. Keim, Daniela Oelke, Royal Truman, Klaus...
RECOMB
2008
Springer
14 years 8 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir
BMCBI
2004
177views more  BMCBI 2004»
13 years 7 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2006
130views more  BMCBI 2006»
13 years 7 months ago
An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution ma
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...