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» Statistical Approach to Networks-on-Chip
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144
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BMCBI
2010
141views more  BMCBI 2010»
15 years 3 months ago
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Franziska Hoffgaard, Philipp Weil, Kay Hamacher
142
Voted
BMCBI
2010
146views more  BMCBI 2010»
15 years 3 months ago
A pairwise residue contact area-based mean force potential for discrimination of native protein structure
Background: Considering energy function to detect a correct protein fold from incorrect ones is very important for protein structure prediction and protein folding. Knowledge-base...
Shahriar Arab, Mehdi Sadeghi, Changiz Eslahchi, Ha...
123
Voted
BMCBI
2010
96views more  BMCBI 2010»
15 years 3 months ago
sdef: an R package to synthesize lists of significant features in related experiments
Background: In microarray studies researchers are often interested in the comparison of relevant quantities between two or more similar experiments, involving different treatments...
Marta Blangiardo, Alberto Cassese, Sylvia Richards...
136
Voted
BMCBI
2010
158views more  BMCBI 2010»
15 years 3 months ago
Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing
Background: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorit...
Corey M. Yanofsky, David R. Bickel
155
Voted
BMCBI
2010
143views more  BMCBI 2010»
15 years 3 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli