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WABI
2010
Springer
167views Bioinformatics» more  WABI 2010»
13 years 7 months ago
Quantifying the Strength of Natural Selection of a Motif Sequence
Quantification of selective pressures on regulatory sequences is a central question in studying the evolution of gene regulatory networks. Previous methods focus primarily on sing...
Chen-Hsiang Yeang
SADM
2010
196views more  SADM 2010»
13 years 3 months ago
Bayesian adaptive nearest neighbor
: The k nearest neighbor classification (k-NN) is a very simple and popular method for classification. However, it suffers from a major drawback, it assumes constant local class po...
Ruixin Guo, Sounak Chakraborty
BMCBI
2006
239views more  BMCBI 2006»
13 years 8 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
PPSN
2000
Springer
14 years 9 days ago
Optimizing through Co-evolutionary Avalanches
Abstract. We explore a new general-purpose heuristic for nding highquality solutions to hard optimization problems. The method, called extremal optimization, is inspired by self-or...
Stefan Boettcher, Allon G. Percus, Michelangelo Gr...
BMCBI
2010
108views more  BMCBI 2010»
13 years 8 months ago
A genetic ensemble approach for gene-gene interaction identification
Background: It has now become clear that gene-gene interactions and gene-environment interactions are ubiquitous and fundamental mechanisms for the development of complex diseases...
Pengyi Yang, Joshua W. K. Ho, Albert Y. Zomaya, Bi...