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BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
WISE
2005
Springer
14 years 1 months ago
Semantic Web Technologies for Interpreting DNA Microarray Analyses: The MEAT System
Abstract. This paper describes MEAT (Memory of Experiments for the Analysis of Transcriptomes), a project aiming at supporting biologists working on DNA microarrays. We provide met...
Khaled Khelif, Rose Dieng-Kuntz, Pascal Barbry
BMCBI
2004
139views more  BMCBI 2004»
13 years 7 months ago
Resolution of large and small differences in gene expression using models for the Bayesian analysis of gene expression levels an
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Jeffrey P. Townsend
BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya
JCB
2006
185views more  JCB 2006»
13 years 7 months ago
A Probabilistic Methodology for Integrating Knowledge and Experiments on Biological Networks
Biological systems are traditionally studied by focusing on a specific subsystem, building an intuitive model for it, and refining the model using results from carefully designed ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...