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BMCBI
2008
88views more  BMCBI 2008»
13 years 9 months ago
Microarray-based gene set analysis: a comparison of current methods
Background: The analysis of gene sets has become a popular topic in recent times, with researchers attempting to improve the interpretability and reproducibility of their microarr...
Sarah Song, Michael A. Black
BMCBI
2004
142views more  BMCBI 2004»
13 years 9 months ago
GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies
Background: Microarray and other high-throughput technologies are producing large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed...
Bing Zhang, Denise Schmoyer, Stefan Kirov, Jay Sno...
BMCBI
2011
13 years 4 months ago
Appearance frequency modulated gene set enrichment testing
Background: Gene set enrichment testing has helped bridge the gap from an individual gene to a systems biology interpretation of microarray data. Although gene sets are defined a ...
Jun Ma, Maureen A. Sartor, H. V. Jagadish
KDD
2003
ACM
180views Data Mining» more  KDD 2003»
14 years 9 months ago
Classifying large data sets using SVMs with hierarchical clusters
Support vector machines (SVMs) have been promising methods for classification and regression analysis because of their solid mathematical foundations which convey several salient ...
Hwanjo Yu, Jiong Yang, Jiawei Han
BMCBI
2008
95views more  BMCBI 2008»
13 years 9 months ago
Gene set analyses for interpreting microarray experiments on prokaryotic organisms
Background: Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Rece...
Nathan L. Tintle, Aaron A. Best, Matthew DeJongh, ...