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BMCBI
2008
100views more  BMCBI 2008»
13 years 7 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
BMCBI
2008
160views more  BMCBI 2008»
13 years 7 months ago
Feature selection environment for genomic applications
Background: Feature selection is a pattern recognition approach to choose important variables according to some criteria in order to distinguish or explain certain phenomena (i.e....
Fabrício Martins Lopes, David Correa Martin...
BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
Mixture models for analysis of melting temperature data
Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
Christoffer Nellåker, Fredrik Uhrzander, Joa...
BMCBI
2008
123views more  BMCBI 2008»
13 years 7 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...