Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Background: Multicategory Support Vector Machines (MC-SVM) are powerful classification systems with excellent performance in a variety of data classification problems. Since the p...
Background: One of the most powerful methods for the prediction of protein structure from sequence information alone is the iterative construction of profile-type models. Because ...
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
Scatter search is an evolutionary method that has been successfully applied to hard optimization problems. The fundamental concepts and principles of the method were first propose...