Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Background: A major goal of cancer research is to identify discrete biomarkers that specifically characterize a given malignancy. These markers are useful in diagnosis, may identi...
Virginie M. Aris, Michael J. Cody, Jeff Cheng, Jam...
We propose a new statistical method for constructing a genetic network from microarray gene expression data by using a Bayesian network. An essential point of Bayesian network con...
Seiya Imoto, SunYong Kim, Takao Goto, Sachiyo Abur...
Background: Gene set enrichment analysis (GSEA) is a microarray data analysis method that uses predefined gene sets and ranks of genes to identify significant biological changes i...
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...