AbstractRecent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of geno...
Abstract. This paper presents a method for regulatory network reconstruction from experimental data. We propose a mathematical model for regulatory interactions, based on the work ...
- Gene regulatory networks allow us to study and understand genes’ roles in biological processes. Among others, regulatory networks help to identify pathway initiator genes and t...
Background: Noise has many important roles in cellular genetic regulatory functions at the nanomolar scale. At present, no good theory exists for identifying all possible mechanis...
The ability to infer parameters of gene regulatory networks is emerging as a key problem in systems biology. The biochemical data are intrinsically stochastic and tend to be observ...
Richard J. Boys, Darren J. Wilkinson, Thomas B. L....