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BMCBI
2004
208views more  BMCBI 2004»
13 years 7 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
COMPSAC
2002
IEEE
14 years 15 days ago
Software Application Platforms: From Product Architecture to Integrated Application Strategy
One promising approach to more effective software development is the concept of product platform originated from mechanical engineering, aiming at architectural product families i...
Markku Sääksjärvi
LAWEB
2003
IEEE
14 years 24 days ago
Application Modeling for the Semantic Web
In this article we present a method for the design and implementation of Web Applications for the Semantic Web. Based on the "Object Oriented Hypermedia Design Method" a...
Fernanda Lima, Daniel Schwabe
BMCBI
2005
138views more  BMCBI 2005»
13 years 7 months ago
Detailed protein sequence alignment based on Spectral Similarity Score (SSS)
Background: The chemical property and biological function of a protein is a direct consequence of its primary structure. Several algorithms have been developed which determine ali...
Kshitiz Gupta, Dina Thomas, S. V. Vidya, K. V. Ven...
RECOMB
2005
Springer
14 years 7 months ago
Recognition of Binding Patterns Common to a Set of Protein Structures
We present a novel computational method, MultiBind, for recognition of binding patterns common to a set of protein structures. It is the first method which performs a multiple alig...
Maxim Shatsky, Alexandra Shulman-Peleg, Ruth Nussi...