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BIB
2008
86views more  BIB 2008»
13 years 10 months ago
Recent developments in the MAFFT multiple sequence alignment program
The accuracy and scalability of multiple sequence alignment (MSA) of DNAs and proteins have long been and are still important issues in bioinformatics. To rapidly construct a reas...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2008
108views more  BMCBI 2008»
13 years 10 months ago
Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks
Background: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications...
David A. Nix, Samir J. Courdy, Kenneth M. Boucher
BMCBI
2006
85views more  BMCBI 2006»
13 years 9 months ago
SVM-based prediction of caspase substrate cleavage sites
Background: Caspases belong to a class of cysteine proteases which function as critical effectors in apoptosis and inflammation by cleaving substrates immediately after unique sit...
Lawrence J. K. Wee, Tin Wee Tan, Shoba Ranganathan
JAIR
2008
103views more  JAIR 2008»
13 years 9 months ago
ICE: An Expressive Iterative Combinatorial Exchange
We present the design and analysis of the first fully expressive, iterative combinatorial exchange (ICE). The exchange incorporates a tree-based bidding language (TBBL) that is co...
Benjamin Lubin, Adam I. Juda, Ruggiero Cavallo, S&...
ALIFE
2005
13 years 9 months ago
Flexible Couplings: Diffusing Neuromodulators and Adaptive Robotics
Recent years have seen the discovery of freely diffusing gaseous neurotransmitters, such as nitric oxide (NO), in biological nervous systems. A type of artificial neural network (A...
Andrew Philippides, Phil Husbands, Tom Smith, Mich...